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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1020 | Doxorubicin hydrochloride | Adriamycin,Doxorubicin (Adriamycin) HCl,Hydroxydaunorubicin hydrochloride,NSC 123127 | Apoptosis , Mitophagy , HBV , HIV Protease , Topoisomerase , Antibacterial , Antibiotic , AMPK , Autophagy |
Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM). Doxorubicin hydrochloride exhibits cytotoxicity and antitum... | |||
T27200 | DOX−NOP1 HCl | doxorubicin-NOP1 conjugate,doxorubicin-NOP1 HCl,DOX−NOP1 Hydrochloride | |
DOX−NOP1 is a molecular hybrid covalently joining doxorubicin (DOX) and NOP1. DOX−NOP1 showed similar increased toxicity toward resistant cancer cells and, in addition, lower cardiotoxicity than DOX. | |||
TQ0049 | MC-DOXHZN hydrochloride | Doxorubicin(6-maleimidocaproyl)hydrazone hydrochloride | Topoisomerase |
MC-DOXHZN hydrochloride is an albumin-binding prodrug of Doxorubicin. Doxorubicin is a DNA topoisomerase II inhibitor. | |||
T11090L1 | Aldoxorubicin hydrochloride | Aldoxorubicin hydrochloride (1361644-26-9 Free base) | Topoisomerase |
Aldoxorubicin hydrochloride is an albumin-binding prodrug of Doxorubicin, a DNA topoisomerase II inhibitor. Aldoxorubicin hydrochloride is released from albumin under acidic conditions. Aldoxorubicin hydrochloride exhibi... | |||
T4247 | I-CBP112 hydrochloride | Epigenetic Reader Domain | |
I-CBP112 is a selective inhibitor of the bromodomain-containing transcription factors. I-CBP112 (1 mM) has little activity against other bromodomains. I-CBP112 targets the CBP/p300 bromodomains. I-CBP112 significantly re... | |||
T40736 | Doxorubicinol hydrochloride | 13-Dihydroadriamycin hydrochloride | |
Doxorubicinol hydrochloride, also known as 13-Dihydroadriamycin hydrochloride, is a secondary alcohol metabolite derived from Doxorubicin. | |||
T71713 | Pirarubicin HCl | ||
Pirarubicin HCl is the hydrochloride salt form of pirarubicin, an analogue of the anthracycline antineoplastic antibiotic doxorubicin with antineoplastic activity. Pirarubicin intercalates into DNA and interacts with top... |